Implementing Sensitive Albuminuria Sensor for Rural Healthcare in Thailand
Thailand's aging society, particularly in rural areas, faces healthcare challenges as younger populations move to cities. Elderly residents often suffer from diabetes and hypertension, making hospital visits difficult. We propose a novel aptasensor for detecting urinary albumin, using DNA aptamer and graphene oxide, with detection limits of 50 ng/mL. Field trials showed 12% of 84 samples had elevated albumin levels, and 50% indicated early kidney dysfunction. This portable, point-of-care sensor can enhance early kidney disease detection and management in rural elderly populations, improving health outcomes.
Authors
- Visarute Pinrod (ORCID: https://orcid.org/0000-0003-2430-5127)
- Ubon Cha’on (ORCID: https://orcid.org/0000-0002-9909-8671)
- Dechnarong Pimalai (ORCID: https://orcid.org/0000-0002-2734-6138)
- Deanpen Japrung (ORCID: https://orcid.org/0000-0003-4206-6641)
- Nuankanya Sathirapongsasuti (ORCID: https://orcid.org/0000-0002-6303-2769)
- Wireeya Chawjiraphan
- Kiatnida Treerattrakoon (ORCID: https://orcid.org/0000-0002-9869-9432)
- Sirirat Anutrakulchai
- Thitirat Putnin
Institutions
- National Science and Technology Development Agency (TH)
- Khon Kaen University (TH)
- Mahidol University (TH)
- National Nanotechnology Center (TH)
- Ramathibodi Hospital (TH)
Publication Details
- Published
- 2024-08-23
- DOI
- https://doi.org/10.1109/i-create62067.2024.10776534
- Primary Topic
- Cardiovascular Health and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Development Agency
- National Nanotechnology Center
- Health Systems Research Institute