Effects of Physical and Psychological Stress Inducement and Combined Activities on Glycemia

Activities and events during daily living can have substantial effects on blood glucose levels in patients with type 1 diabetes. We evaluate the glycemic effects of different physical and psychological stress inducements and combined activities based on clinical data. The average change in blood glucose levels were −18, −15 and −10 mg/dL for cycling, running and resistance exercise, respectively. In some scenarios, psychological stress inducement activities showed an increase in glucose levels that warrant further exploration. The developed model is able to reproduce the self-reported insulin-to-carb ratios with a Pearson correlation coefficient of 0.86. Understanding the glycemic response to physical and psychological stressors will enable more effective therapy for people with type 1 diabetes.