Intrauterine blood transfusion causes dose- and time-dependent signal alterations in the liver and the spleen on fetal magnetic resonance imaging

Question What fetal changes are found by MRI after life-saving intrauterine transfusion (IUT)? Findings Dose- and time-dependent reductions in signal intensity of the fetal liver and spleen, as well as hepatosplenomegaly, were found after intrauterine transfusion. Clinical relevance Intrauterine transfusions cause transient iron overload with consequential changes in MRI signal intensity of fetal livers and spleens. Fetal hepatosplenomegaly can be expected following transfusions. Radiologists' awareness of changes following IUT may improve report quality.

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Publication Details

Journal
European Radiology
Published
2024-12-11
DOI
https://doi.org/10.1007/s00330-024-11228-y
Primary Topic
Fetal and Pediatric Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Intrauterine blood transfusion causes dose- and time-dependent signal alterations in the liver and the spleen on fetal magnetic resonance imaging

Victor Ulrich Schmidbauer, Michael Schwarz, Jakob Kittinger, Patric Kienast et al.
European Radiology
Fetal and Pediatric Neurological Disorders
article

Intrauterine blood transfusion causes dose- and time-dependent signal alterations in the liver and the spleen on fetal magnetic resonance imaging

Victor Ulrich Schmidbauer, Michael Schwarz, Jakob Kittinger, Patric Kienast, Marlene Stuempflen, Caroline Schwarz, Herbert Kiss, Gregor J. Kasprian, Dieter Bettelheim, Julia Binder, C. Haberl, Thomas Reiberger, Martin L. Watzenboeck, Daniela Prayer, Nikolaus Michael Nowak, J Malik
article en

Abstract

Question What fetal changes are found by MRI after life-saving intrauterine transfusion (IUT)? Findings Dose- and time-dependent reductions in signal intensity of the fetal liver and spleen, as well as hepatosplenomegaly, were found after intrauterine transfusion. Clinical relevance Intrauterine transfusions cause transient iron overload with consequential changes in MRI signal intensity of fetal livers and spleens. Fetal hepatosplenomegaly can be expected following transfusions. Radiologists' awareness of changes following IUT may improve report quality.

European RadiologyVol. 35(3)
Medical University of Vienna (AT)
Universität Wien, Medizinische Universität Wien
Openalex Percentile: Top 65%
Fetal and Pediatric Neurological Disorders
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Intrauterine blood transfusion causes dose- and time-dependent signal alterations in the liver and the spleen on fetal magnetic resonance imaging — Victor Ulrich Schmidbauer, Michael Schwarz, et al. · European Radiology (2024) | TGRS Research Map | TGRS