Numerical Algorithm of Effective Cancer Treatment Based on the Fisher-Kolmogorov Equation
An inverse extremal problem for the Fisher-Kolmogorov model of tumor growth is studied. It is required to minimize the normalized density of tumor cells in a given subdomain, while the drug concentration in the tissue must be limited to specified values. The solvability of the inverse extremal problem is established. An algorithm to find its solution is constructed. The numerical experiments illustrate its efficiency.
Authors
- Andrey Kovtanyuk (ORCID: https://orcid.org/0000-0002-3286-110X)
- Christina Kuttler (ORCID: https://orcid.org/0000-0002-5521-4159)
- A. Yu. Chebotarëv (ORCID: https://orcid.org/0000-0002-6456-9138)
Publication Details
- Journal
- EPiC series in computing
- Published
- 2024-12-11
- DOI
- https://doi.org/10.29007/z3mk
- Primary Topic
- Mathematical Biology Tumor Growth
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Science and Higher Education of the Russian Federation