Flowsheet Testing for Separation of Lutetium-177 from an Irradiated Ytterbium Target
The results of an experiment to verify a complex technology for isolation of 177Lu from an irradiated 1-g ytterbium target are presented. The main components of the experimental installation, which is mounted in a research hot cell, are described. These components include the extraction and separation of lutetium and ytterbium, the evaporation and preconcentration of 177Lu, and its chromatographic purification. The feasibility of obtaining a pharmaceutical substance no carrier added lutetium-177 trichloride that meets the standards set by the European Pharmacopoeia has been confirmed.
Authors
- A. A. Naumov
- E. A. Puzikov
- A. M. Prokoshin
- I.A. Ushakov (ORCID: https://orcid.org/0000-0002-3821-5176)
- E. V. Ambul
- М. V. Mamchich
- V. V. Zukau
- N. D. Goletskiy
- S. A. Rodionov (ORCID: https://orcid.org/0000-0002-9661-8221)
- Н. В. Ковалев
- Н. А. Семенова
- E. O. Zagladkin
- N. A. Dedov
Institutions
- National Research Tomsk State University (RU)
- V. G. Khlopin Radium Institute (RU)
- Tomsk Polytechnic University (RU)
- St. Petersburg State Technological Institute (RU)
Publication Details
- Journal
- Radiochemistry
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1134/s1066362224050047
- Citations
- 2
- Primary Topic
- Extraction and Separation Processes
- Type
- article
- Field-Weighted Citation Impact
- 0.43