Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

This study highlights Paromomycin's potential as a therapeutic agent for GBM by targeting HDAC1-mediated SUMOylation pathways and influencing IGF1R translocation, warranting further investigation for its clinical application.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2024-12-11
DOI
https://doi.org/10.3389/fphar.2024.1490878
Citations
3
Primary Topic
Histone Deacetylase Inhibitors Research
Type
article
Field-Weighted Citation Impact
0.70
Controls
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article

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Min Zhong, Yuejie Guo, Ning Luo
3 citations
Frontiers in Pharmacology
Histone Deacetylase Inhibitors Research
0.70
article

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Min Zhong, Yuejie Guo, Ning Luo
article en
3 citations

Abstract

This study highlights Paromomycin's potential as a therapeutic agent for GBM by targeting HDAC1-mediated SUMOylation pathways and influencing IGF1R translocation, warranting further investigation for its clinical application.

Frontiers in PharmacologyVol. 15
Chenzhou First People's Hospital (CN)
Openalex Percentile: Top 28%
Histone Deacetylase Inhibitors Research
0.70
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Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma — Min Zhong, Yuejie Guo, et al. · Frontiers in Pharmacology (2024) | TGRS Research Map | TGRS