Comprehensive plasma metabolomics analysis of berberine treatment in ulcerative colitis rats by LC-MS/MS
This study provided valuable insights into the mechanism by which berberine exerted its therapeutic effects on UC through metabolomics. Our results highlighted berberine's potential to modulate key metabolic pathways and restore the levels of several metabolites, suggesting its utility as a therapeutic agent for UC. These findings underscored the importance of metabolomics in understanding the pathophysiology and treatment of UC.
Authors
- Lingyi Xin
- Xuemei Wei (ORCID: https://orcid.org/0000-0001-9761-5586)
- Qinhua Chen (ORCID: https://orcid.org/0000-0002-9108-1314)
- Zhiming Yang
- Li Wang (ORCID: https://orcid.org/0000-0002-8009-9746)
- Yang Yang (ORCID: https://orcid.org/0000-0002-1529-4975)
- Liang Yu (ORCID: https://orcid.org/0009-0007-3922-3454)
- Renyan Liu (ORCID: https://orcid.org/0009-0009-5676-3350)
- Linqi Su
- Baodong Feng
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Hubei University of Medicine (CN)
Publication Details
- Journal
- Frontiers in Chemistry
- Published
- 2024-12-11
- DOI
- https://doi.org/10.3389/fchem.2024.1518110
- Citations
- 1
- Primary Topic
- Berberine and alkaloids research
- Type
- article
- Field-Weighted Citation Impact
- 0.45