The safety profile of usage of glucagon‐like peptide‐1 receptor agonists in pregnancy: A pharmacovigilance analysis based on the Food and Drug Administration Adverse Event Reporting System

This study highlights increasing GLP-1 RA use in pregnant women and identifies potential pregnant ADRs. GLP-1 RAs are not recommended for use during pregnancy. In cases of unintentional exposure, close monitoring is advised to ensure maternal and foetal safety. These findings provide valuable insights for clinicians making informed decisions and regulators considering using GLP-1 RA in pregnancy.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2024-12-10
DOI
https://doi.org/10.1111/bcp.16354
Citations
10
Primary Topic
Pharmacovigilance and Adverse Drug Reactions
Type
article
Field-Weighted Citation Impact
3.51
Controls
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article

The safety profile of usage of glucagon‐like peptide‐1 receptor agonists in pregnancy: A pharmacovigilance analysis based on the Food and Drug Administration Adverse Event Reporting System

Xuemei Wu, Maobai Liu, Zipeng Wei, Jianxing Zhou et al.
10 citations
British Journal of Clinical Pharmacology
Pharmacovigilance and Adverse Drug Reactions
3.51
article

The safety profile of usage of glucagon‐like peptide‐1 receptor agonists in pregnancy: A pharmacovigilance analysis based on the Food and Drug Administration Adverse Event Reporting System

Xuemei Wu, Maobai Liu, Zipeng Wei, Jianxing Zhou, Weipeng Lai
article en
10 citations

Abstract

This study highlights increasing GLP-1 RA use in pregnant women and identifies potential pregnant ADRs. GLP-1 RAs are not recommended for use during pregnancy. In cases of unintentional exposure, close monitoring is advised to ensure maternal and foetal safety. These findings provide valuable insights for clinicians making informed decisions and regulators considering using GLP-1 RA in pregnancy.

British Journal of Clinical PharmacologyVol. 91(4)
Fujian Medical University (CN), Union Hospital (CN)
Good health and well-being
Openalex Percentile: Top 7%
Pharmacovigilance and Adverse Drug Reactions
3.51
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