Insulin like growth factor 2 mRNA binding protein 2 regulates vascular development in cerebral arteriovenous malformations
Our findings suggest that IGF2BP2, via m<sup>6</sup>A-dependent regulation of LGALS8, is crucial for vascular development and presents potential targets for therapeutic intervention in cerebral AVMs.
Authors
- Sha Xie (ORCID: https://orcid.org/0000-0001-5160-6799)
- Lin-Jian Wang (ORCID: https://orcid.org/0000-0002-7054-6397)
- Hongkai Lian (ORCID: https://orcid.org/0000-0002-6630-3077)
- Yangyang Wu (ORCID: https://orcid.org/0000-0002-6801-7429)
Institutions
- Henan Tianguan Group (China) (CN)
- Zhengzhou Central Hospital (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-12-11
- DOI
- https://doi.org/10.3389/fneur.2024.1483016
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China