Evaluation of the Incidence of Nocardia Infection in Solid Organ Transplant Recipients on Trimethoprim-Sulfamethoxazole for Opportunistic Infection Prophylaxis
Our findings suggest that OI prophylaxis with TMP-SMX may be protective against nocardiosis in SOT recipients. If possible, patients who are switched to an alternative agent due to TMP-SMX intolerance should be re-challenged when the adverse effect resolves. Most patients in our study were able to tolerate re-initiation, suggesting that the adverse effects associated with TMP-SMX may be temporary and may not warrant discontinuation.
Authors
- Christina Ruggia-Check
- R. C. Jung (ORCID: https://orcid.org/0000-0003-0589-4544)
- Ishani Shah (ORCID: https://orcid.org/0000-0003-2916-1089)
- Jenny Au (ORCID: https://orcid.org/0009-0008-6418-1687)
- Jacqueline Burnell (ORCID: https://orcid.org/0000-0002-5456-1087)
- Adam Diamond (ORCID: https://orcid.org/0000-0002-0319-4627)
Institutions
- Lahey Hospital and Medical Center (US)
- Lahey Medical Center (US)
- Temple University Hospital (US)
- Temple University (US)
Publication Details
- Journal
- Annals of Pharmacotherapy
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1177/10600280241302412
- Citations
- 1
- Primary Topic
- Actinomycetales infections and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.57