Kaempferol Review on pharmacological action in treatment of various diseases

Since millions of years ago, medicinal plants have been a major source of therapeutic medicines. The majority of medications that have been found are either natural ingredients or their derivatives. It is a true reality that nature is the source of an apparently infinite variety of molecule configurations. These structures can be enhanced to create scaffolds of innovative medications for the treatment of a variety of illnesses. They are also rich sources for the production of robust chemotypes and pharmacophores. "Natural products" refers to substances originating from plants, marine organisms, bread molds, microorganisms, and both terrestrial and invertebrate animals. These compounds are recognized for their remarkable drug-like qualities and wide range of chemical compositions, which support their multi-targeted action. These substances include flavonoids that include benzopyran and hydroxyphenyl groups, i.e. Flavonoid compound kaempferol, sometimes referred to as kaempferol 3 or kaempferide, is found naturally in tea and a variety of common fruits and vegetables, such as gooseberries, beans, broccoli, and cabbage. The major goal of this study is to provide an overview of the numerous pharmacological actions of kaempferol in treating disorders, as well as the ongoing research into the underlying mechanisms. Numerous acute and chronic inflammation-induced illnesses, such as colitis and inter­-vertebral disc degeneration, as well as postmenopausal bone loss and acute lung injury, may be treated with it. Moreover, it protects the heart and brain function, inhibits vascular endothelial inflammation, fights cancer, liver damage, obesity, and diabetes, and may be used to treat fibro proliferative illnesses like hypertrophic scar.    

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Publication Details

Journal
African Journal of Biomedical Research
Published
2024-09-20
DOI
https://doi.org/10.53555/ajbr.v27i3.4818
Primary Topic
Computational Drug Discovery Methods
Type
article
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article

Kaempferol Review on pharmacological action in treatment of various diseases

M Saranya
African Journal of Biomedical Research
Computational Drug Discovery Methods
article

Kaempferol Review on pharmacological action in treatment of various diseases

M Saranya
article en

Abstract

Since millions of years ago, medicinal plants have been a major source of therapeutic medicines. The majority of medications that have been found are either natural ingredients or their derivatives. It is a true reality that nature is the source of an apparently infinite variety of molecule configurations. These structures can be enhanced to create scaffolds of innovative medications for the treatment of a variety of illnesses. They are also rich sources for the production of robust chemotypes and pharmacophores. "Natural products" refers to substances originating from plants, marine organisms, bread molds, microorganisms, and both terrestrial and invertebrate animals. These compounds are recognized for their remarkable drug-like qualities and wide range of chemical compositions, which support their multi-targeted action. These substances include flavonoids that include benzopyran and hydroxyphenyl groups, i.e. Flavonoid compound kaempferol, sometimes referred to as kaempferol 3 or kaempferide, is found naturally in tea and a variety of common fruits and vegetables, such as gooseberries, beans, broccoli, and cabbage. The major goal of this study is to provide an overview of the numerous pharmacological actions of kaempferol in treating disorders, as well as the ongoing research into the underlying mechanisms. Numerous acute and chronic inflammation-induced illnesses, such as colitis and inter­-vertebral disc degeneration, as well as postmenopausal bone loss and acute lung injury, may be treated with it. Moreover, it protects the heart and brain function, inhibits vascular endothelial inflammation, fights cancer, liver damage, obesity, and diabetes, and may be used to treat fibro proliferative illnesses like hypertrophic scar.    

African Journal of Biomedical Research
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Computational Drug Discovery Methods
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