Contraceptives or Hormone Replacement Therapy and Associations with Autoimmune Conditions: Exploring Effects of Estrogen Analog Supplementation
Combined estrogen and progesterone therapy is associated with an increased risk of several autoimmune conditions. The role of estrogen, despite its protective effects against some conditions, underscores the complex interplay of sex hormones in autoimmunity. Further prospective studies are needed to elucidate underlying mechanisms and evaluate causality.
Authors
- Yurilú Andreina González-Moret (ORCID: https://orcid.org/0000-0002-6134-6385)
- Diego Lema (ORCID: https://orcid.org/0000-0001-7910-1127)
- Irakli Tskhakaia (ORCID: https://orcid.org/0009-0002-6785-9744)
- Nanuka Tsibadze
- Arthur Lau (ORCID: https://orcid.org/0000-0002-4876-761X)
- Andy Palmer
- M. Carolina Musri (ORCID: https://orcid.org/0000-0002-3821-8115)
Institutions
- Johns Hopkins University (US)
- Johns Hopkins Bayview Medical Center (US)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1002/acr2.11774
- Citations
- 4
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.15