Differential response to immunotherapy in different lesions of MSI-H double primary colorectal cancer: a case report and literature review

Specific histological subtypes of CRC, such as mucinous adenocarcinoma, might adversely affect the efficacy of immunotherapy, resulting in primary treatment resistance. Consequently, in the case of this particular cancer subtype, local surgical resection may be a more appropriate treatment strategy.

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Publication Details

Journal
AME Case Reports
Published
2024-12-11
DOI
https://doi.org/10.21037/acr-24-137
Citations
6
Primary Topic
Multiple and Secondary Primary Cancers
Type
article
Field-Weighted Citation Impact
2.32

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article

Differential response to immunotherapy in different lesions of MSI-H double primary colorectal cancer: a case report and literature review

Yajing Su, Shenyong Su, Yingde Wang, Zhiyu Wang et al.
6 citations
AME Case Reports
Multiple and Secondary Primary Cancers
2.32
article

Differential response to immunotherapy in different lesions of MSI-H double primary colorectal cancer: a case report and literature review

Yajing Su, Shenyong Su, Yingde Wang, Zhiyu Wang, Lin An, Yan Shi, Zhigui Guo, Yue Huo, Dan Hong, Yaning Wei
article en
6 citations

Abstract

Specific histological subtypes of CRC, such as mucinous adenocarcinoma, might adversely affect the efficacy of immunotherapy, resulting in primary treatment resistance. Consequently, in the case of this particular cancer subtype, local surgical resection may be a more appropriate treatment strategy.

AME Case ReportsVol. 9
Affiliated Hospital of Hebei University (CN), Baoding People's Hospital (CN)
Hebei University
Good health and well-being
Openalex Percentile: Top 10%
Multiple and Secondary Primary Cancers
2.32
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