Molecular characterization and antimicrobial susceptibility for 62 isolates of Bordetella pertussis from children
This work showed that there may be a link between antimicrobial resistance and alterations in specific molecular types, and the isolates showed a clear change when compared with the vaccine strain and that selection pressure from both antibiotics and immunization may be responsible for driving Chinese BP evolution, and necessitate a reevaluation of the immunization strategy and the development of novel vaccines in China to halt the resurgence and medication resistance of pertussis.
Authors
- Ruoxuan Wang
- Wen-Chao Zhang (ORCID: https://orcid.org/0000-0002-3128-8460)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-5464-1626)
- Haixia Zhang (ORCID: https://orcid.org/0000-0003-1453-6503)
- Hongbin Zhang (ORCID: https://orcid.org/0000-0002-2516-2634)
- Baohua He
- Leyu Wang (ORCID: https://orcid.org/0000-0002-6547-1490)
- Fei Zheng (ORCID: https://orcid.org/0000-0003-3513-4255)
- Sun Yin-qi
- Zhaoyi Jia
- Su-xia Duan
Institutions
- North China University of Science and Technology (CN)
- Hospital of Hebei Province (CN)
- National Institute for Communicable Disease Control and Prevention (CN)
- Hebei Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-12-11
- DOI
- https://doi.org/10.3389/fmicb.2024.1498638
- Citations
- 5
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Health Commission of Hebei Province