Resveratrol and β-hydroxy-β-methylbutyric acid supplementation promotes ileal development and digestive function by altering microbial community abundance and metabolites in Tibetan sheep

In summary, our results suggested that RES and (or) HMB supplementation improved SCFAs concentration by up-regulating the microbial community abundance (<i>Brevibacillus</i>, <i>Clostridium sensu stricto 3</i>, and <i>Eubacterium hallii group</i>) and metabolism (L-arginine, butanoic acid, D-mannose, and retinol), thus contributing to ileal morphology and digestive enzyme activity. These findings may provides a novel reference for the nutritional regulation to improve the production of Tibetan sheep.