Real life data of ONC201 (dordaviprone) in pediatric and adult H3K27-altered recurrent diffuse midline glioma: Results of an international academia-driven compassionate use program
While the efficacy of ONC201 needs validation in a controlled randomized clinical trial, our real-life data support a better outcome for patients with thalamic tumors treated with ONC201. We demonstrated furthermore the feasibility of a successful academia-driven compassionate use program.
Authors
- Franck Bourdeaut (ORCID: https://orcid.org/0000-0001-9489-6781)
- Imene Hezam
- Isabelle Yoldjian
- André Rieutord (ORCID: https://orcid.org/0000-0001-5935-7635)
- Élodie Vauléon (ORCID: https://orcid.org/0000-0001-9019-9778)
- G. Vassal
- Michael Capra (ORCID: https://orcid.org/0000-0001-5982-1944)
- Maxime Annereau (ORCID: https://orcid.org/0000-0001-9594-2516)
- Émilie De Carli
- V. Salomon
- Daniela Di Carlo (ORCID: https://orcid.org/0000-0003-0573-8576)
- Marc Sanson (ORCID: https://orcid.org/0000-0002-1813-8476)
- Virginie Gandemer (ORCID: https://orcid.org/0000-0002-4991-233X)
- Liora Brunel
- Samuel Abbou (ORCID: https://orcid.org/0000-0002-7159-8869)
- S. Jacobs
- Marina Vignes
- David Guyon
- Sarah Dumont
- Nicolas Epaillard (ORCID: https://orcid.org/0000-0001-7543-491X)
- Jacques Grill
- Lucas Denis
- Mehdi Touat (ORCID: https://orcid.org/0000-0002-2340-5604)
- Françoise Duperray
- X. Baiao
- F. Lemos
Institutions
- Centre National de la Recherche Scientifique (FR)
- University of Padua (IT)
- Inserm (FR)
- Duquesne University (US)
- Université Paris-Saclay (FR)
- Institut Gustave Roussy (FR)
- Children's Health Ireland at Crumlin (IE)
- Centre Hospitalier Universitaire de Lille (FR)
- Sorbonne Université (FR)
- Agence Nationale de Sécurité du Médicament et des Produits de Santé (FR)
- Centre Hospitalier Universitaire d'Angers (FR)
- Institut de génétique et de développement de Rennes (FR)
- Institut du Cerveau (FR)
- Centre Hospitalier Universitaire de Rennes (FR)
- Prédicteurs moléculaires et nouvelles cibles en oncologie
- Université d'Angers (FR)
- Institut Curie (FR)
- KU Leuven (BE)
Publication Details
- Journal
- European Journal of Cancer
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1016/j.ejca.2024.115165
- Citations
- 11
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.82
Funders
- Amsterdam University Medical Centers