Screening the Subsistence of Bacterial Propagation in Different Units of Tertiary Hospitals in Bangladesh Along with Their Drug Susceptible Pattern

Abstract BACKGROUND: Antibiotic resistance is concerning since it has been associated with higher mortality and healthcare expenditures, especially for patients, physicians, and the healthcare system. In order to address the significant issue of antibiotic-resistant patterns of pathogen, the current research aimed to isolate hospital-acquired bacterial stains from the premises of many private and public medical college hospitals in Dhaka, Bangladesh, India. MATERIALS AND METHODS: To conduct this study, the samples were collected from different units, for example, intensive care unit, general ward, gynecological ward, emergency ward and outdoor unit, employing swab technique method, and transferred aseptically in the Microbiology Laboratory of Stamford University Bangladesh. The drug-resistant profile of the isolates was estimated through the disk-diffusion method. RESULTS: The pattern of resistance of the isolates was clearly evident against seven different antibiotics such as cefexime (5 μg), ciprofloxacin (5 μg), Co-Trimoxazole (25 μg), cefuroxime (30 μg), gentamycin (10 μg), nalidixic acid (30 μg), and Polymyxin B (300 μg). According to our findings, Staphylococcus spp., Escherichia coli, Klebsiella spp., Bacillus anthracis , and Haemophilus influenza showed resistance against all the antibiotics except gentamycin (10 μg). CONCLUSION: The study revealed the multidrug resistance in clinically identified pathogens which is very alarming and could be the prime reason for spading the nosocomial infection.