The effect of silk short fiber biomimetic materials on the recovery of sports function in patients with meniscal injury during sports

BackgroundIn sports, especially high-intensity and high-risk activities, the meniscus is easily damaged. For patients with meniscus injuries, it is necessary to repair or replace the patient's meniscus. However, as age increases, the human meniscus tissue gradually forms and cannot be repaired through its own meniscus. Therefore, it is necessary to maintain the patient's movement function through meniscus support materials.ObjectiveTraditional meniscus support materials have poor mechanical properties and poor biocompatibility. In response to this issue, this study designed a meniscus scaffold made of silk short fibers, silk fibroin, and wool protein.MethodsThrough electrospinning and freeze-drying techniques, the material was processed to obtain a silk short fiber meniscus with a biomimetic structure.ResultsThrough experiments, the surface morphology, hydrophobicity, porosity, secondary structure, thermal stability, water absorption swelling, and MP of MCS made of SSF biomimetic materials were characterized.ConclusionThe experimental results show that the manufactured silk short fiber meniscus has good compressive performance, thermal stability, and water absorption and swelling properties, and it also exhibits good biocompatibility.

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Publication Details

Journal
Bio-Medical Materials and Engineering
Published
2024-12-11
DOI
https://doi.org/10.1177/09592989241296427
Primary Topic
Silk-based biomaterials and applications
Type
article
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article

The effect of silk short fiber biomimetic materials on the recovery of sports function in patients with meniscal injury during sports

Dongsong Bin, Yong Wang
Bio-Medical Materials and Engineering
Silk-based biomaterials and applications
article

The effect of silk short fiber biomimetic materials on the recovery of sports function in patients with meniscal injury during sports

Dongsong Bin, Yong Wang
article en

Abstract

BackgroundIn sports, especially high-intensity and high-risk activities, the meniscus is easily damaged. For patients with meniscus injuries, it is necessary to repair or replace the patient's meniscus. However, as age increases, the human meniscus tissue gradually forms and cannot be repaired through its own meniscus. Therefore, it is necessary to maintain the patient's movement function through meniscus support materials.ObjectiveTraditional meniscus support materials have poor mechanical properties and poor biocompatibility. In response to this issue, this study designed a meniscus scaffold made of silk short fibers, silk fibroin, and wool protein.MethodsThrough electrospinning and freeze-drying techniques, the material was processed to obtain a silk short fiber meniscus with a biomimetic structure.ResultsThrough experiments, the surface morphology, hydrophobicity, porosity, secondary structure, thermal stability, water absorption swelling, and MP of MCS made of SSF biomimetic materials were characterized.ConclusionThe experimental results show that the manufactured silk short fiber meniscus has good compressive performance, thermal stability, and water absorption and swelling properties, and it also exhibits good biocompatibility.

Bio-Medical Materials and EngineeringVol. 36(2)
Guangxi University (CN)
Openalex Percentile: Top 89%
Silk-based biomaterials and applications
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The effect of silk short fiber biomimetic materials on the recovery of sports function in patients with meniscal injury during sports — Dongsong Bin, Yong Wang · Bio-Medical Materials and Engineering (2024) | TGRS Research Map | TGRS