Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence Assay and Its Application to Disposition and Biliary Excretion Kinetics

A validated method was developed and found to be specific, precise and accurate. The applicability of this proposed method was substantiated in pharmacokinetic studies in rats.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2024-12-01
DOI
https://doi.org/10.2147/dddt.s476173
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
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article

Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence Assay and Its Application to Disposition and Biliary Excretion Kinetics

Chen‐Hsi Chou, Wei-Chun Wang, Ching‐Ling Cheng, Cheng‐Yuan Tsai et al.
Drug Design Development and Therapy
Antibiotics Pharmacokinetics and Efficacy
article

Determination of Nemonoxacin in Small Volumes of Rat Plasma and Bile by a Novel HPLC-Fluorescence Assay and Its Application to Disposition and Biliary Excretion Kinetics

Chen‐Hsi Chou, Wei-Chun Wang, Ching‐Ling Cheng, Cheng‐Yuan Tsai, Ruei-Lin Wu
article en

Abstract

A validated method was developed and found to be specific, precise and accurate. The applicability of this proposed method was substantiated in pharmacokinetic studies in rats.

Drug Design Development and TherapyVol. Volume 18
Tzu Chi University (TW), TaiGen Biotechnology (Taiwan) (TW), National Cheng Kung University (TW)
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Openalex Percentile: Top 78%
Antibiotics Pharmacokinetics and Efficacy
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