Causal association between sarcopenia and cognitive impairment contributes to the muscle–brain axis: A bidirectional Mendelian randomization study
The results of our MR investigation revealed a definitive cause-and-effect association between SP and CI. Our findings provide additional supporting evidence for the muscle-brain axis, which may suggest that muscle strengthening has a significant impact on the management and avoidance of CI. Geriatr Gerontol Int 2025; 25: 116-122.
Authors
- Hao-Ming Li (ORCID: https://orcid.org/0000-0001-7815-6484)
- Shiyin Li (ORCID: https://orcid.org/0000-0001-9635-7079)
- Lincheng Duan (ORCID: https://orcid.org/0000-0003-1937-1605)
- Yue Shi (ORCID: https://orcid.org/0000-0002-9250-3005)
- Yue Feng (ORCID: https://orcid.org/0000-0002-0899-9918)
Institutions
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Geriatrics and gerontology international/Geriatrics & gerontology international
- Published
- 2024-12-11
- DOI
- https://doi.org/10.1111/ggi.15045
- Citations
- 5
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.63