<scp>CCN1</scp> Promotes Mesenchymal Phenotype Transition Through Activating <scp>NF</scp>‐<scp>κB</scp> Signaling Pathway Regulated by <scp>S100A8</scp> in Glioma Stem Cells
Our findings reveal that CCN1 may be an important factor in the enhanced invasiveness and MES phenotype transition of GSCs and highlight the potential to target CCN1 for treating GBM.
Authors
- Zijie Gao (ORCID: https://orcid.org/0009-0002-8974-5633)
- Fan Yang (ORCID: https://orcid.org/0000-0003-0717-5420)
- Xing Guo (ORCID: https://orcid.org/0000-0001-8431-8590)
- Shuo Xu (ORCID: https://orcid.org/0000-0002-7839-8552)
- Chuanxin Wang (ORCID: https://orcid.org/0000-0002-3796-6293)
- Shuhua Guo (ORCID: https://orcid.org/0009-0007-9872-9332)
- Feng Tian
Institutions
- Shandong University (CN)
- Second Hospital of Shandong University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1111/cns.70128
- Citations
- 4
- Primary Topic
- Connective Tissue Growth Factor Research
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Key Technology Research and Development Program of Shandong
- National Key Research and Development Program of China
- Science and Technology Support Plan for Youth Innovation of Colleges and Universities of Shandong Province of China