Repair Effect of siRNA Double Silencing of the Novel Mechanically Sensitive Ion Channels Piezo1 and TRPV4 on an Osteoarthritis Rat Model
Double silencing Piezo1 and TRPV4 plays a key role in cartilage repair in an osteoarthritic rat model by promoting the expression of Aggrecan and Collagen II.
Authors
- Zhuqing Jia (ORCID: https://orcid.org/0000-0002-8329-9911)
- Xiaofei Li (ORCID: https://orcid.org/0000-0001-5143-9652)
- Qining Yang (ORCID: https://orcid.org/0000-0001-5439-5229)
- Jianguo Han
- Jibin Wang (ORCID: https://orcid.org/0009-0005-9128-3716)
Institutions
- Weifang Medical University (CN)
- Jinhua Central Hospital (CN)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2024-12-10
- DOI
- https://doi.org/10.2174/0118761429317745241017114020
- Citations
- 12
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- Medical Science and Technology Project of Zhejiang Province
- Natural Science Foundation of Zhejiang Province