Interleukin-4 promotes the clearance of amyloid-β by monocyte through enhancing the recognition and intracellular processing of amyloid-β
Our study supports the role of IL-4 in regulating Aβ clearance and inflammatory response by monocytes, suggesting that IL-4 may have therapeutic potential for AD.
Authors
- Yan‐Jiang Wang (ORCID: https://orcid.org/0000-0002-6227-6112)
- Yi‐Fei Ji (ORCID: https://orcid.org/0000-0001-9518-0486)
- Yuan Cheng (ORCID: https://orcid.org/0000-0002-1707-8184)
- Sihan Chen (ORCID: https://orcid.org/0000-0002-2890-9764)
Institutions
- North Sichuan Medical University (CN)
- Army Medical University (CN)
- Fudan University (CN)
- Daping Hospital (CN)
- Nanchong Central Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1177/13872877241295361
- Citations
- 5
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- National Natural Science Foundation of China
- Department of Science and Technology of Sichuan Province