Long-term hypoxic atmosphere enhances the stemness, immunoregulatory functions, and therapeutic application of human umbilical cord mesenchymal stem cells
Our results demonstrate that Hy-MSCs possess immense potential for clinical applications via promoting stemness maintenance and enhancing immunoregulatory function.
Authors
- Youqiong Zhuo
- Shao-Yong Fan
- Zhongxin Duan
- Yueyan Huang
- Jianan Wang (ORCID: https://orcid.org/0009-0007-8301-780X)
- Zhou-Hang Zhang
- Xiaohan Zhang (ORCID: https://orcid.org/0000-0003-4360-2995)
- Ke-Yu Deng (ORCID: https://orcid.org/0000-0003-4802-5074)
- Y.-C. Long (ORCID: https://orcid.org/0009-0006-5724-469X)
- Qiming Huang
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Nanchang University (CN)
- Lushan Botanical Garden (CN)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2024-12-12
- DOI
- https://doi.org/10.1302/2046-3758.1312.bjr-2024-0136.r2
- Citations
- 5
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 2.19
Funders
- Jiangxi Provincial Department of Science and Technology
- National Key Research and Development Program of China