Early progressive disease within 2 years in isocitrate dehydrogenase (IDH)–mutant astrocytoma may indicate radiation necrosis

Radiation necrosis should be considered in cases showing early progression of isocitrate dehydrogenase-mutant astrocytoma, and a second surgery should be performed to confirm true recurrence or radiation necrosis. Astrocytomas with telomerase reverse-transcriptase promoter mutations may relapse relatively early and should be followed up with caution.

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Publication Details

Journal
Japanese Journal of Clinical Oncology
Published
2024-12-11
DOI
https://doi.org/10.1093/jjco/hyae151
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Early progressive disease within 2 years in isocitrate dehydrogenase (IDH)–mutant astrocytoma may indicate radiation necrosis

Akihiko Yoshida, Yuko Kubo, Mai Honda‐Kitahara, Hirokazu Sugino et al.
Japanese Journal of Clinical Oncology
Glioma Diagnosis and Treatment
article

Early progressive disease within 2 years in isocitrate dehydrogenase (IDH)–mutant astrocytoma may indicate radiation necrosis

Akihiko Yoshida, Yuko Kubo, Mai Honda‐Kitahara, Hirokazu Sugino, Tomohiro Hosoya, Kenkichi Masutomi, Shunsuke Yanagisawa, Kaishi Satomi, Hiroshi Igaki, Yasuji Miyakita, Makoto Ohno, Akihide Kondo, Yukie Ozeki, Masamichi Takahashi, Koichi Ichimura, Yoshitaka Narita, Tomoyuki Nakano, Hiromichi Suzuki, Miu Kikuchi
article en

Abstract

Radiation necrosis should be considered in cases showing early progression of isocitrate dehydrogenase-mutant astrocytoma, and a second surgery should be performed to confirm true recurrence or radiation necrosis. Astrocytomas with telomerase reverse-transcriptase promoter mutations may relapse relatively early and should be followed up with caution.

Japanese Journal of Clinical OncologyVol. 55(2)
Tokai University (JP), Kyorin University (JP), Juntendo University (JP), National Cancer Center (US), Tokai University Hospital (JP), Saitama Cancer Center (JP), National Cancer Center Hospital East (JP), Tokyo National Hospital (JP), National Cancer Research Institute (GB)
Japan Agency for Medical Research and Development
Openalex Percentile: Top 57%
Glioma Diagnosis and Treatment
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