Diagnostic Test Characteristics of Ultrasound-Based Hydronephrosis for Chronic Kidney Disease in Children and Adolescents With Myelomeningocele: Results From the UMPIRE and National Spina Bifida Patient Registry Cohort Studies
In 2 cohorts of children and youth with myelomeningocele, hydronephrosis conferred a sensitivity of ∼25% for a creatinine-based eGFR < 90 mL/min/1.73 m<sup>2</sup>. This low sensitivity suggests that hydronephrosis alone is a poor screening marker of kidney health.
Authors
- Tonya Williams (ORCID: https://orcid.org/0000-0002-8175-7579)
- M. Chad Wallis (ORCID: https://orcid.org/0000-0001-8977-8406)
- Tiebin Liu (ORCID: https://orcid.org/0000-0002-9456-061X)
- David B. Joseph (ORCID: https://orcid.org/0000-0002-6924-6450)
- Douglass B. Clayton (ORCID: https://orcid.org/0000-0003-4460-4167)
- Evalynn Vasquez (ORCID: https://orcid.org/0000-0002-0530-4690)
- David I. Chu (ORCID: https://orcid.org/0000-0002-7972-4671)
- Earl Y. Cheng (ORCID: https://orcid.org/0000-0002-0799-1738)
- Elizabeth Rőth (ORCID: https://orcid.org/0000-0002-2392-7330)
- John S. Wiener (ORCID: https://orcid.org/0000-0003-4764-8018)
- Jacqueline Mix (ORCID: https://orcid.org/0000-0001-6418-7706)
- Stacy T. Tanaka (ORCID: https://orcid.org/0000-0002-3169-1858)
- Elizabeth B. Yerkes (ORCID: https://orcid.org/0000-0003-2680-9118)
- Jennifer Ahn (ORCID: https://orcid.org/0000-0002-8108-2794)
- Duong D. Tu (ORCID: https://orcid.org/0000-0001-9592-8925)
- Michelle A. Baum (ORCID: https://orcid.org/0000-0002-5517-7650)
- J. Christopher Austin (ORCID: https://orcid.org/0000-0002-4785-8093)
- Jonathan C. Routh (ORCID: https://orcid.org/0000-0002-7731-963X)
- Susan Jarosz
Institutions
- Children's Hospital of Wisconsin (US)
- Boston Children's Hospital (US)
- Centers for Disease Control and Prevention (US)
- Lurie Children's Hospital (US)
- Seattle Children's Hospital (US)
- Monroe Carell Jr. Children's Hospital (US)
- University of Minnesota (US)
- Children's Hospital of Los Angeles (US)
- Oregon Health & Science University (US)
- Medical College of Wisconsin (US)
- University of Utah (US)
- Children's of Alabama (US)
- Duke Medical Center (US)
- Texas Children's Hospital (US)
- Duke University Hospital (US)
Publication Details
- Journal
- The Journal of Urology
- Published
- 2025-02-07
- DOI
- https://doi.org/10.1097/ju.0000000000004342
- Citations
- 1
- Primary Topic
- Spinal Dysraphism and Malformations
- Type
- article
- Field-Weighted Citation Impact
- 1.88