[Analysis of the emergency standard ischemic stroke care system time points for in-hospital-onset ischemic stroke and community-onset stroke in general hospital].

<b>Objective:</b> To analyze the treatment situation at each time node in the standard in-hospital-stroke(IHS) in the general hospital compared with that in the emergency(community)-onset stroke (COS) group. <b>Methods:</b> A single-center retrospective case-control study was performed.The clinical cases of acute COS group and IHS group who were treated by the same stroke green channel team at Peking Union Medical College Hospital from Jan.2021 to Apr.2024 were included. The treatment process of acute stage of stroke was divided into four time nodes (onset, recognition, admission, and treatment), and the time of each time node was compared and analyzed. <b>Results:</b> A total of 219 ischemic stroke cases were included, comprising 83 and 136 cases in IHS and COS groups, respectively. There were 134 male patients (61.2%) with a mean onset age of (66.3±15.1) years. IHS occurred across various departments, mainly in surgical departments(55/83, 66.2%). Of the perioperative IHS events, 93.7% (45/48) occurred after the surgery. Compared with the COS group, the IHS group showed a higher rate of post-waking stroke[11/32(34.4%) vs 18/136(13.2%), <i>P</i>=0.004], a lower rate of intravenous thrombolysis[9/32 (29.0%) vs 128/136 (94.8%), <i>P</i>0.001], and a higher rate of mechanical thrombectomy [11/32(34.4%) vs 4/136 (2.9%), <i>P</i>0.001].The overall median onset-CT time in the IHS group was shorter than that in the COS group[<i>M</i> (<i>Q</i>₁, <i>Q</i>₃)] [100 (59, 189)min vs 135(75, 210)min, <i>P</i>=0.030]. In different stages, median time from stroke onset to recognition[25(1, 140) vs 1(1, 30)min,<i>P</i>=0.005] and the on-site/reception CT [30 (19, 40) min vs 16 (11, 26) min, <i>P</i>=0.001] in the IHS group were longer than those in the COS group, while the median time from recognition to admission[30 (10, 48) min vs 76 (53, 137)min, P0.001]was shorter than that in the COS group. <b>Conclusions:</b> By using the standard ischemic stroke care system, the overall treatment time for IHS group is shorter than that of COS groups. However, compared with COS patients, the onset-recognition and admission to examination/treatment time was significantly prolonged for IHS patients, reflecting the need for further optimization of the standardized in-hospital stroke treatment process.