Circulating Proneurotensin Levels Predict Impaired Bone Mineralisation in Postmenopausal Women With Type 2 Diabetes Mellitus
In women with T2D, greater proNT levels are associated with impaired bone mineralisation and predict mineral density decline overtime. ProNT could potentially serve as a diagnostic tool for identifying patients at higher risk of osteopenia/osteoporosis, suggesting a significant connection between this neuropeptide and bone metabolism in diabetes.
Authors
- Vittorio Venditti (ORCID: https://orcid.org/0000-0003-1707-2687)
- Flavia Agata Cimini (ORCID: https://orcid.org/0000-0001-7630-7349)
- Giulia Passarella
- Federica Sentinelli (ORCID: https://orcid.org/0000-0002-5379-0590)
- Ilaria Barchetta (ORCID: https://orcid.org/0000-0003-0530-8568)
- Susanna Morano (ORCID: https://orcid.org/0000-0002-8156-9543)
- Tiziana Filardi (ORCID: https://orcid.org/0000-0001-5002-0753)
- Sara Dule (ORCID: https://orcid.org/0000-0002-5089-6963)
- Andrea Lenzi (ORCID: https://orcid.org/0000-0002-7711-0465)
- Maria Gisella Cavallo (ORCID: https://orcid.org/0000-0001-6630-8049)
- Enrico Bleve (ORCID: https://orcid.org/0000-0003-1659-6796)
- Elisabetta Romagnoli (ORCID: https://orcid.org/0000-0002-6298-9235)
- Marco Giorgio Baroni (ORCID: https://orcid.org/0000-0002-3224-6078)
- Olle Melander (ORCID: https://orcid.org/0000-0002-2581-484X)
- Alessandro Oldani
Institutions
- Lund University (SE)
- University of L'Aquila (IT)
- Istituto Neurologico Mediterraneo (IT)
- Skåne University Hospital (SE)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Diabetes/Metabolism Research and Reviews
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1002/dmrr.70018
- Citations
- 1
- Primary Topic
- Neuropeptides and Animal Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.27
Funders
- Ministero della Salute
- Agenzia Italiana del Farmaco, Ministero della Salute