Metabonomic Biomarkers of Plaque Burden and Instability in Patients With Coronary Atherosclerotic Disease After Moderate Lipid‐Lowering Therapy
Our findings highlight the potential of nuclear magnetic resonance-based metabolomics in identifying novel biomarkers of plaque burden and instability. Metabolites related to plaque burden may facilitate noninvasive assessment of CAD prognosis.
Authors
- Chenhao Lin (ORCID: https://orcid.org/0000-0001-5102-801X)
- Lingfeng Luo (ORCID: https://orcid.org/0000-0002-0601-0053)
- Mengyao Yu (ORCID: https://orcid.org/0000-0002-5346-535X)
- Shalaimaiti Shali (ORCID: https://orcid.org/0000-0001-6842-3956)
- Guo‐Chong Chen (ORCID: https://orcid.org/0000-0003-1853-6244)
- Juying Qian (ORCID: https://orcid.org/0000-0002-7512-3692)
- Runda Wu
- Zhendong Mei (ORCID: https://orcid.org/0000-0001-6235-8647)
- Huiru Tang (ORCID: https://orcid.org/0000-0002-7139-2756)
- Yan Zheng (ORCID: https://orcid.org/0000-0003-1129-3147)
- Qingxia Huang (ORCID: https://orcid.org/0000-0001-6549-2737)
- Zhonghan Sun (ORCID: https://orcid.org/0000-0003-4171-9794)
- Zhen Wang (ORCID: https://orcid.org/0000-0001-9289-4889)
- Junbo Ge (ORCID: https://orcid.org/0000-0002-9360-7332)
- Lili Xu (ORCID: https://orcid.org/0000-0001-8212-6157)
- Liang Sun
- Hongyi Wu (ORCID: https://orcid.org/0000-0003-4773-1962)
- Yijing Lu (ORCID: https://orcid.org/0000-0002-0171-2611)
- Kang Yao (ORCID: https://orcid.org/0000-0003-3178-8470)
- Yuxiang Dai (ORCID: https://orcid.org/0000-0003-2479-8996)
Institutions
- Fudan University (CN)
- Soochow University (CN)
- Zhongshan Hospital (CN)
- YangPu Geriatric Hospital (CN)
- State Key Laboratory of Genetic Engineering
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1161/jaha.124.036906
- Citations
- 12
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.81
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Shanghai Hospital Development Center
- Shanghai Clinical Research Center
- Program of Shanghai Academic Research Leader