Study of the association of markers of central and peripheral arterial stiffness with renal function in patients with arterial hypertension, diabetes mellitus and chronic kidney disease
Aortic stiffness increases in the presence of vascular risk factors such as hypertension, DM and CKD. This increase is greater when DM and CKD coexist. Increased aortic stiffness is inversely associated with GFR and directly with uALB, and is predictive of decreased GFR and abnormal uALB. The VP<sub>c-f</sub> is the parameter of aortic stiffness that is most consistently associated with renal dysfunction. Increased aortic stiffness could be one of the pathomechanisms linking renal dysfunction to cardiovascular events.
Authors
- Alfredo Michán‐Doña (ORCID: https://orcid.org/0000-0002-4373-6224)
- Pablo Gómez-Fernández
- Rafael Santamaría (ORCID: https://orcid.org/0000-0002-2627-1445)
- Josefina Gálvez Moral
- Jary Perelló Martínez
- Juan Carlos Hidalgo Santiago
Institutions
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Fernández-Vega Ophthalmological Institute (ES)
- Hospital Universitario de Burgos (ES)
- Biomedical Research and Innovation Institute of Cadiz (ES)
- Hospital Jerez Puerta del Sur (ES)
Publication Details
- Journal
- Nefrología (English Edition)
- Published
- 2024-11-01
- DOI
- https://doi.org/10.1016/j.nefroe.2024.11.018
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00