Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation

These findings reveal that acute GLP-1R agonism can disrupt electrical signaling and induce arrhythmia in aged mice through CK2 hyperphosphorylation, providing new insights into the cardiovascular effects of GLP-1RAs in the elderly.

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Publication Details

Journal
The Anatolian Journal of Cardiology
Published
2024-12-10
DOI
https://doi.org/10.14744/anatoljcardiol.2024.4719
Citations
4
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
Field-Weighted Citation Impact
1.61
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article

Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation

Yusuf Olğar
4 citations
The Anatolian Journal of Cardiology
Cardiac electrophysiology and arrhythmias
1.61
article

Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation

Yusuf Olğar
article en
4 citations

Abstract

These findings reveal that acute GLP-1R agonism can disrupt electrical signaling and induce arrhythmia in aged mice through CK2 hyperphosphorylation, providing new insights into the cardiovascular effects of GLP-1RAs in the elderly.

The Anatolian Journal of CardiologyVol. 29(2)
Ankara University (TR)
Zero hunger
Openalex Percentile: Top 14%
Cardiac electrophysiology and arrhythmias
1.61
DOIOpen Access PDFOpenAlex
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Acute GLP-1 Agonism Induces Arrhythmogenic Electrical Activity in Aged Mice Heart Through Impaired Cellular Na+ and Ca2+ Handlings: The Role of CK2 Hyperphosphorylation — Yusuf Olğar · The Anatolian Journal of Cardiology (2024) | TGRS Research Map | TGRS