Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids

The accurate and rapid diagnosis of bacterial vaginosis (BV) is crucial due to its high prevalence and association with serious health complications, including increased risk of sexually transmitted infections and adverse pregnancy outcomes. Although widely used, traditional diagnostic methods have significant limitations in subjectivity, complexity, and cost. The development of a novel diagnostic approach that integrates SERS with ML offers a promising solution. The CNN model's high prediction accuracy, cost-effectiveness, and extraordinary rapidity underscore its significant potential to enhance the diagnosis of BV in clinical settings. This method not only addresses the limitations of current diagnostic tools but also provides a more accessible and reliable option for healthcare providers, ultimately enhancing patient care and health outcomes.

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Publication Details

Journal
mSystems
Published
2024-12-10
DOI
https://doi.org/10.1128/msystems.01058-24
Citations
9
Primary Topic
Reproductive tract infections research
Type
article
Field-Weighted Citation Impact
3.10

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article

Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids

Quan Yuan, Muhammad Usman, Hui-Jin Chen, Jia‐Wei Tang et al.
9 citations
mSystems
Reproductive tract infections research
3.10
article

Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids

Quan Yuan, Muhammad Usman, Hui-Jin Chen, Jia‐Wei Tang, Huimin Chen, Yudong Zhang, Liang Wang, Xin‐Ru Wen, Yu-Rong Tang, Jie Chen
article en
9 citations

Abstract

The accurate and rapid diagnosis of bacterial vaginosis (BV) is crucial due to its high prevalence and association with serious health complications, including increased risk of sexually transmitted infections and adverse pregnancy outcomes. Although widely used, traditional diagnostic methods have significant limitations in subjectivity, complexity, and cost. The development of a novel diagnostic approach that integrates SERS with ML offers a promising solution. The CNN model's high prediction accuracy, cost-effectiveness, and extraordinary rapidity underscore its significant potential to enhance the diagnosis of BV in clinical settings. This method not only addresses the limitations of current diagnostic tools but also provides a more accessible and reliable option for healthcare providers, ultimately enhancing patient care and health outcomes.

mSystemsVol. 10(1)
Edith Cowan University (AU), Xuzhou Medical College (CN), The University of Western Australia (AU), Shengli Oilfield Central Hospital (CN), Guangdong Academy of Medical Sciences (CN), Guangdong Provincial People's Hospital (CN), Southern Medical University (CN)
National Natural Science Foundation of China, Basic and Applied Basic Research Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 8%
Reproductive tract infections research
3.10
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