Investigating LETd optimization strategies in carbon ion radiotherapy for pancreatic cancer: a dosimetric study using an anthropomorphic phantom
This study demonstrated the feasibility of enhancing LETd in pancreatic tumors using carbon ion arc delivery coupled with LETd optimization. The possibility of delivering these plans was verified through irradiation of an anthropomorphic pancreas phantom, which showed agreement between dose measurements and predictions.
Authors
- Jakob Liermann (ORCID: https://orcid.org/0000-0002-1445-1940)
- Christina Stengl (ORCID: https://orcid.org/0000-0003-0273-0878)
- Thomas Tessonnier (ORCID: https://orcid.org/0000-0002-8919-4299)
- Friderike K. Longarino (ORCID: https://orcid.org/0009-0003-7531-3757)
- Filipa Baltazar (ORCID: https://orcid.org/0009-0003-9848-6642)
- Jürgen Debus (ORCID: https://orcid.org/0000-0002-6411-4811)
- Stewart Mein (ORCID: https://orcid.org/0000-0002-6480-912X)
- Andrea Mairani (ORCID: https://orcid.org/0000-0001-6669-7064)
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Oncological Hadrontherapy (IT)
- National Center for Tumor Diseases (DE)
- National Institutes for Quantum Science and Technology (JP)
- Deutsches Konsortium für Translationale Krebsforschung (DE)
Publication Details
- Journal
- Medical Physics
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1002/mp.17569
- Citations
- 6
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 2.51