Synthesis, characterization and docking studies of Sliver(I)- -Nheterocyclic carbene ligated Schiff base complexes

This study presents the synthesis, characterization, and molecular docking studies of a novel Schiff base functionalized N-heterocyclic carbene. The synthesis involved the coordination of Schiff Base/NHC ligand precursor (1M) with silver(I) ions, yielding Silver(I)- Schiff base /NHC Complex (1N). Characterization of (1M) and(1N) were performed using various spectroscopic techniques, including NMR, IR and UV-Vis, supplemented by elemental analysis. Molecular docking studies were conducted to explore potential biological activities of the synthesized complex. The results demonstrate successful synthesis of the Schiff base functionalized NHC complex of silver(I) and provide valuable insights into its structural properties and potential biological applications.

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Publication Details

Journal
Journal of Kufa for Chemical Sciences
Published
2024-11-01
DOI
https://doi.org/10.36329/jkcm/2024/v3.i3.16066
Primary Topic
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
Type
article
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article

Synthesis, characterization and docking studies of Sliver(I)- -Nheterocyclic carbene ligated Schiff base complexes

Mustafa Naji Mohammed Saleh, Mohammed Z. Ghadhyeb
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Journal of Kufa for Chemical Sciences
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
article

Synthesis, characterization and docking studies of Sliver(I)- -Nheterocyclic carbene ligated Schiff base complexes

Mustafa Naji Mohammed Saleh, Mohammed Z. Ghadhyeb
article en

Abstract

This study presents the synthesis, characterization, and molecular docking studies of a novel Schiff base functionalized N-heterocyclic carbene. The synthesis involved the coordination of Schiff Base/NHC ligand precursor (1M) with silver(I) ions, yielding Silver(I)- Schiff base /NHC Complex (1N). Characterization of (1M) and(1N) were performed using various spectroscopic techniques, including NMR, IR and UV-Vis, supplemented by elemental analysis. Molecular docking studies were conducted to explore potential biological activities of the synthesized complex. The results demonstrate successful synthesis of the Schiff base functionalized NHC complex of silver(I) and provide valuable insights into its structural properties and potential biological applications.

Journal of Kufa for Chemical SciencesVol. 3(3)
University of Kufa (IQ)
Clean water and sanitation
Openalex Percentile: Top 83%
N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
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