Construction, Anticancer Assessment and Spectral Study of Novel Cycles-Triazole Derivatives

Triazoles play an essential role in pharmacy, especially when exposed to the chemical structure of the drug, delving into drug metabolism processes, and biological preparations. It is found abundantly in vitamins, dyes and many other natural products. Most heterogeneous organic compounds are extracted from animal or plant sources. It is used in some industries, such as the manufacture of nylon used in the clothing industry, and in the manufacture of vitamin C. It represents the active group in many enzymes, coenzymes, polymers, and the manufacture of nucleic acids. The study also reached the grades of diagnosing and determining the structural formula using the infrared spectrum (FT-IR), the proton magnetic resonance spectrum (1H-NMR), and the carbon nuclear magnetic resonance spectrum (13C-NMR) according to the functional groups and their appearance in each spectrum. Also, when comparing the process of preparing the derivatives, it was found the difference in the substituted groups from the base compound has a clear effect on the time period for completion of the reaction, which was monitored using the TLC -technique, in addition to the difference in effectiveness as a result of the difference in these groups. The efficiency of some breeders in inhibiting breast cancer cells and cells affected by the tumour was also evaluated and characterized.