Synthesis, Identification some of new heterocyclic Compounds Derivatives and study of the biological Activity
This research includes prepeared of some new heterocyclic compounds from 2-hydroxy napthaldehyde with 2-amino thiazol , 2-amino thiazol reacted with 2-hydroxy napthaldehyde , to produce shiff base derivative (R),(R) using to synthesis of some new heterocyclic derivatives by reactions and reactant with types solvent and materials to synthesis heterocyclic membered ring , first step : Involved synthesis of seven heterocyclic compounds by reacting (R) with phthalic ,succinic and malic anhydride respectfully to prepeared oxazepine compounds (R1,R2,R3) . Second step involves preparing of five- heterocyclic derivatives by reacting (R) with amino acid glycine and thyrocine in tetra hydro furan to prepare (R4,R5).Third step includes preparing of four heterocyclic compounds β-lactam(S6). All the compounds were characterized by FT-IR ,H1NMR,13CNMR .Also compounds were studied the measurement antibacterial activity.
Authors
- Rusul Ali Muhammad
- Rajaa Abdulameer Ghafil
Publication Details
- Journal
- Journal of Kufa for Chemical Sciences
- Published
- 2024-11-01
- DOI
- https://doi.org/10.36329/jkcm/2024/v3.i3.15932
- Primary Topic
- Synthesis of β-Lactam Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00