Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study
Our data imply that acupuncture ameliorates overall cognitive function, along with changes in brain activity, gut microbiota, and serum metabolites, providing preliminary evidence of the mechanisms acting through the MGB axis underlying the effects of acupuncture on aMCI.
Authors
- Qiong-Nan Bao (ORCID: https://orcid.org/0000-0002-2350-5381)
- Zi-Wen Chen
- Ling Zhao (ORCID: https://orcid.org/0000-0002-3955-0072)
- Kexin Wu (ORCID: https://orcid.org/0000-0002-9445-9538)
- Zi-Han Yin
- Xinyue Zhang (ORCID: https://orcid.org/0000-0001-9773-7137)
- Yiwei Liu
- Ziqi Wang (ORCID: https://orcid.org/0009-0007-6701-5177)
- Xia He (ORCID: https://orcid.org/0000-0001-5527-5990)
- Fang Ye (ORCID: https://orcid.org/0000-0002-2615-9074)
- Jin Yao (ORCID: https://orcid.org/0000-0003-3028-9370)
- Wanqi Zhong
- Fanrong Liang (ORCID: https://orcid.org/0000-0001-8518-9268)
- Yaqin Li (ORCID: https://orcid.org/0000-0003-2363-4834)
Institutions
- Sichuan University (CN)
- The Fourth People's Hospital (CN)
- West China Hospital of Sichuan University (CN)
- Fourth People's Hospital of Sichuan Province (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Complementary Therapies in Medicine
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1016/j.ctim.2024.103118
- Citations
- 9
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.94