Untargeted Metabolomics Reveals the Role of Lipocalin-2 in the Pathological Changes of Lens and Retina in Diabetic Mice
Numerous metabolites exhibited substantial alterations in the lenses and retinas of diabetic mice. Untargeted metabolomics has provided insights into the function of LCN2 in DC and DR. These changes in metabolites, along with their related pathways, could be the mechanisms by which LCN2 modulated DC and DR.
Authors
- Jian Jiang (ORCID: https://orcid.org/0000-0002-0579-5194)
- Tianyi Kang (ORCID: https://orcid.org/0009-0002-2352-2082)
- Cong Fan (ORCID: https://orcid.org/0000-0002-9603-1594)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-2460-5392)
- Yang Yu (ORCID: https://orcid.org/0000-0002-5481-5382)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1167/iovs.65.14.19
- Citations
- 3
- Primary Topic
- Advanced Glycation End Products research
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- National Natural Science Foundation of China
- Central South University
- Xiangya Hospital, Central South University