Oral Squamous Cell Carcinoma and What We Lose During Formalin Fixation: An Evaluation of Changes in Macroscopic Resection Margins Utilizing Virtual Three-Dimensional Imaging Techniques with Analysis Based on 947 Measurements
Formalin fixation (FF) caused the shrinkage of the OSCC MRM, particularly in tongue cancers. Even after proper surgical excision in the postoperative results, the number of normal MRMs was underestimated. This should be considered when interpreting the results of surgical treatment. However, FF had a minimal impact on the overall shrinkage of the tumors themselves.
Authors
- Tomasz Wach (ORCID: https://orcid.org/0000-0003-4763-8354)
- Maciej Sikora (ORCID: https://orcid.org/0000-0002-3348-1950)
- Adam Michcik (ORCID: https://orcid.org/0000-0003-4727-0799)
- Adam Polcyn (ORCID: https://orcid.org/0000-0002-9340-6856)
- Rafał Pęksa (ORCID: https://orcid.org/0000-0002-4904-7059)
- Barbara Drogoszewska (ORCID: https://orcid.org/0000-0003-0144-8483)
- Maksym A. Jopek (ORCID: https://orcid.org/0000-0002-7530-2199)
- Paolo Iacoviello (ORCID: https://orcid.org/0000-0002-7767-4164)
- Giovanni Audino (ORCID: https://orcid.org/0000-0003-2652-4198)
- Łukasz Garbacewicz (ORCID: https://orcid.org/0000-0001-6851-7223)
- B. Wojciechowska (ORCID: https://orcid.org/0000-0003-4003-1170)
- Piotr Choma
Institutions
- Ente Ospedaliero Ospedali Galliera (IT)
- Medical University of Lodz (PL)
- Ministry of Interior and Administration (PL)
- Gdańsk Medical University (PL)
- Pomeranian Medical University (PL)
Publication Details
- Journal
- Biomedicines
- Published
- 2024-12-10
- DOI
- https://doi.org/10.3390/biomedicines12122805
- Citations
- 3
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 1.21