Research progress in the application of microfluidic chip <?A3B2 pi6?>technology for infectious disease diagnosis

<p indent="0mm">Infectious diseases, characterized by high pathogenicity and rapid transmission, pose a serious threat to human health. Rapid and accurate pathogen identification is crucial for effective treatment and prevention. Microfluidic chip technology has emerged as a versatile tool in clinical diagnostics, molecular detection, and personalized medicine. By integrating microfluidic platforms with various detection methods, this technology addresses the urgent need for rapid diagnosis of multiple pathogens, offering the potential to revolutionize and advance the diagnosis and research of infectious disease. This review explores the wide-ranging applications of microfluidic chip technology in the clinical diagnosis of infectious diseases, including pathogen detection, analysis of host immune responses, antibody screening, and its role in cellular immune response studies and proteomics. Additionally, we highlight the real-time detection capabilities of microfluidic chips, emphasizing their advantages in terms of high sensitivity, low cost, high throughput, speed, and user-friendliness. This review aims to provide a foundation for advancing scientific research and practical applications in the rapid detection of infectious diseases.

Authors

Publication Details

Journal
Scientia Sinica Vitae
Published
2024-12-01
DOI
https://doi.org/10.1360/ssv-2024-0304
Primary Topic
Biosensors and Analytical Detection
Type
article
Field-Weighted Citation Impact
0.00
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article

Research progress in the application of microfluidic chip &lt;?A3B2 pi6?&gt;technology for infectious disease diagnosis

Junping Peng, Xin Zhang
Scientia Sinica Vitae
Biosensors and Analytical Detection
article

Research progress in the application of microfluidic chip &lt;?A3B2 pi6?&gt;technology for infectious disease diagnosis

Junping Peng, Xin Zhang
article en

Abstract

<p indent="0mm">Infectious diseases, characterized by high pathogenicity and rapid transmission, pose a serious threat to human health. Rapid and accurate pathogen identification is crucial for effective treatment and prevention. Microfluidic chip technology has emerged as a versatile tool in clinical diagnostics, molecular detection, and personalized medicine. By integrating microfluidic platforms with various detection methods, this technology addresses the urgent need for rapid diagnosis of multiple pathogens, offering the potential to revolutionize and advance the diagnosis and research of infectious disease. This review explores the wide-ranging applications of microfluidic chip technology in the clinical diagnosis of infectious diseases, including pathogen detection, analysis of host immune responses, antibody screening, and its role in cellular immune response studies and proteomics. Additionally, we highlight the real-time detection capabilities of microfluidic chips, emphasizing their advantages in terms of high sensitivity, low cost, high throughput, speed, and user-friendliness. This review aims to provide a foundation for advancing scientific research and practical applications in the rapid detection of infectious diseases.

Scientia Sinica Vitae
Openalex Percentile: Top 79%
Biosensors and Analytical Detection
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