Real-world data of first-line treatment with pembrolizumab for NSCLC with high PD-L1 expression in elderly patients: a subgroup analysis of HOT/NJLCG2001
Some elderly patients with NSCLC and high PD-L1 expression might benefit from COMB; however, MONO is considered the preferred treatment. MONO may not be an effective or feasible treatment for patients with PS 2-3, even with high PD-L1 expression.
Authors
- Ryo Morita (ORCID: https://orcid.org/0000-0002-2843-7736)
- Daisuke Jingu (ORCID: https://orcid.org/0000-0002-0153-3912)
- Motoki Sekikawa (ORCID: https://orcid.org/0009-0005-5637-5199)
- Hidenori Mizugaki (ORCID: https://orcid.org/0000-0003-1167-2497)
- Toshihiko Agatsuma (ORCID: https://orcid.org/0000-0001-6535-5230)
- Fumiaki Yoshiike
- Kazunari Tateishi (ORCID: https://orcid.org/0000-0003-4641-640X)
- Hajime Kikuchi
- Toshiyuki Sumi (ORCID: https://orcid.org/0000-0002-2540-5878)
- Hiroshi Yokouchi (ORCID: https://orcid.org/0000-0001-5964-0051)
- Yasuyuki Ikezawa (ORCID: https://orcid.org/0000-0002-8054-6091)
- Kyoji Tsurumi (ORCID: https://orcid.org/0009-0005-3363-424X)
- Tsutomu Hachiya
- Hiroshi Yamamoto (ORCID: https://orcid.org/0000-0002-4056-9264)
- Keiki Yokoo (ORCID: https://orcid.org/0009-0008-8576-4750)
- Mari Aso
- Nozomu Kimura (ORCID: https://orcid.org/0009-0002-4596-0964)
- Keiichi Nakamura
- Atsushi Nakamura (ORCID: https://orcid.org/0000-0002-5248-636X)
- Furuta Megumi
- Makoto Kosaka
- Yasuo Kitamura
Institutions
- Shinshu University (JP)
- Asahikawa Medical University (JP)
- Tohoku University (JP)
- Sapporo University (JP)
- Hokkaido University (JP)
- Muroran Institute of Technology (JP)
- Nagano Prefectural Suzaka Hospital (JP)
- Showa General Hospital (JP)
- Ikeda Municipal Hospital (JP)
- Miyagi Prefectural Hospital Organization (JP)
- Kameda Medical Center (JP)
- Oji General Hospital (JP)
- Nagano Municipal Hospital (JP)
- Yamagata Prefectural Central Hospital (JP)
- The Cancer Institute Hospital (JP)
- National Hospital Organization (JP)
- Akita Industrial Technology Center (JP)
- Teine Keijinkai Hospital (JP)
- Hakodate National Hospital (JP)
- Suwa Red Cross Hospital (JP)
- Kushiro City General Hospital (JP)
- Sendai Kousei Hospital (JP)
- Japanese Foundation For Cancer Research (JP)
Publication Details
- Journal
- Japanese Journal of Clinical Oncology
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1093/jjco/hyae168
- Citations
- 2
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.57