Effect of low-dose administration of carperitide for acute heart failure: the LASCAR-AHF trial
In patients with AHF, low-dose carperitide did not reduce long-term mortality or hospitalization events when combined with standard treatment. Because patient enrolment was terminated prematurely, the study was underpowered and inconclusive.
Authors
- Hirotada Maeda (ORCID: https://orcid.org/0009-0006-3182-2156)
- Satoshi Yasuda (ORCID: https://orcid.org/0000-0002-7470-5236)
- Hiroki Nakano (ORCID: https://orcid.org/0000-0003-1487-3702)
- Atsushi Mizuno (ORCID: https://orcid.org/0000-0002-7596-7633)
- Takanori Kawabata (ORCID: https://orcid.org/0000-0001-9208-4659)
- Satoshi Honda (ORCID: https://orcid.org/0000-0002-1393-4270)
- Yasuyuki Honda (ORCID: https://orcid.org/0000-0002-6710-9890)
- Toshiyuki Nagai (ORCID: https://orcid.org/0000-0002-1043-0608)
- Toshihisa Anzai (ORCID: https://orcid.org/0000-0003-3319-4967)
- Takafumi Yamane
- Teruo Noguchi (ORCID: https://orcid.org/0000-0001-5372-4932)
- Yasuhide Asaumi (ORCID: https://orcid.org/0000-0002-9009-7234)
- Koko Asakura
- Yutaka Furukawa (ORCID: https://orcid.org/0000-0003-4585-2437)
- Naotsugu Iwakami (ORCID: https://orcid.org/0000-0002-1378-900X)
- Tetsuo Yamaguchi (ORCID: https://orcid.org/0000-0002-9641-4894)
- Yusuke Tokuda
- Takeshi Kitai (ORCID: https://orcid.org/0000-0003-2416-5865)
- Sakae Takenaka (ORCID: https://orcid.org/0009-0004-3295-0243)
- Yoshiya Kato
- Shuzo Nishihara
Institutions
- Tokyo Medical University (JP)
- Tohoku University (JP)
- Hokkaido University (JP)
- St. Luke's International Hospital (JP)
- National Cerebral and Cardiovascular Center (JP)
- Hyogo Brain and Heart Center (JP)
- Hakodate National Hospital (JP)
- Kushiro City General Hospital (JP)
- Kobe City Medical Center General Hospital (JP)
- Toranomon Hospital (JP)
Publication Details
- Journal
- European Heart Journal Acute Cardiovascular Care
- Published
- 2024-12-04
- DOI
- https://doi.org/10.1093/ehjacc/zuae140
- Citations
- 6
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 2.41
Funders
- Japan Research Foundation for Clinical Pharmacology
- Japan Cardiovascular Research Foundation