Finerenone, Obesity, and Heart Failure With Mildly Reduced/Preserved Ejection Fraction
In patients with HF with mildly reduced/preserved ejection fraction, the beneficial effects of finerenone on clinical events and symptoms were consistent, irrespective of BMI at baseline, possibly with a greater effect on the primary outcome in patients with higher BMI. (FINEARTS-HF [FINerenone trial to investigate Efficacy and sAfety superioR to placebo in paTientS with Heart Failure]; NCT04435626).
Authors
- Mark C. Petrie (ORCID: https://orcid.org/0000-0002-6333-9496)
- Brian Lee Claggett (ORCID: https://orcid.org/0000-0002-4215-9218)
- Cândida Fonseca (ORCID: https://orcid.org/0000-0003-3019-5956)
- Johann Bauersachs (ORCID: https://orcid.org/0000-0002-9341-117X)
- Pardeep S. Jhund (ORCID: https://orcid.org/0000-0003-4306-5317)
- James Lay‐Flurrie
- John J.V. McMurray (ORCID: https://orcid.org/0000-0002-6317-3975)
- Alasdair Henderson (ORCID: https://orcid.org/0000-0002-8903-4906)
- Jawad H. Butt (ORCID: https://orcid.org/0000-0002-7380-4144)
- Faiez M. Zannad (ORCID: https://orcid.org/0000-0001-7456-1570)
- Gerard C.M. Linssen (ORCID: https://orcid.org/0000-0002-3339-1955)
- Bertram Pitt (ORCID: https://orcid.org/0000-0001-5880-275X)
- Michele Senni (ORCID: https://orcid.org/0000-0001-5502-7882)
- Muthiah Vaduganathan (ORCID: https://orcid.org/0000-0003-0885-1953)
- Andrea Lage
- Subodh Verma (ORCID: https://orcid.org/0000-0002-4018-8533)
- Adriaan A. Voors
- Sanjiv J. Shah (ORCID: https://orcid.org/0000-0002-5655-8201)
- Mikhail Kosiborod
- Morten Schou
- Scott D Solomon
- Akshay S. Desai
- Markus F. Scheerer
- Prabhakar Viswanathan
Institutions
- Northwestern University (US)
- Brigham and Women's Hospital (US)
- St. Michael's Hospital (CA)
- University Medical Center Groningen (NL)
- Harvard University (US)
- Bayer (United States) (US)
- Inserm (FR)
- National University of Singapore (SG)
- University of Toronto (CA)
- University of Michigan (US)
- Gentofte Hospital (DK)
- British Heart Foundation (GB)
- Endo Pharmaceuticals (United States) (US)
- Medizinische Hochschule Hannover (DE)
- Ospedale Papa Giovanni XXIII (IT)
- National University Heart Centre Singapore (SG)
- Saint Luke's Hospital (US)
- National Heart Centre Singapore (SG)
- Ziekenhuis Groep Twente (NL)
- Bayer (United Kingdom) (GB)
- Bayer (Germany) (DE)
- University of Missouri–Kansas City (US)
- University of Glasgow (GB)
- Universidade Nova de Lisboa (PT)
- Université de Lorraine (FR)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1016/j.jacc.2024.10.111
- Citations
- 37
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 13.23
Funders
- Pharmaceuticals Bayer