Anti-integrin αvβ6 Antibodies Predict Pouchitis in Patients With Ulcerative Colitis After Restorative Proctocolectomy With Ileal Pouch-Anal Anastomosis
The anti-integrin αvβ6 antibody levels in patients with UC were decreased after RPC but remained high in patients who developed pouchitis. The antibody levels at the time of RPC may serve as a potential prognostic biomarker for predicting the risk of pouchitis in patients with UC.
Authors
- Hajime Yamazaki (ORCID: https://orcid.org/0000-0002-9034-4370)
- Hiroshi Seno (ORCID: https://orcid.org/0000-0002-8509-8128)
- Masataka Yokode (ORCID: https://orcid.org/0000-0003-0751-0188)
- Yoshihiro Nishikawa (ORCID: https://orcid.org/0000-0002-1113-6937)
- Takafumi Yanaidani (ORCID: https://orcid.org/0000-0003-0621-3982)
- Masahiro Shiokawa (ORCID: https://orcid.org/0000-0001-6436-3888)
- Risa Nakanishi
- Norimitsu Uza (ORCID: https://orcid.org/0000-0002-1334-5740)
- Yuya Muramoto (ORCID: https://orcid.org/0000-0001-5159-8397)
- Sakiko Ota (ORCID: https://orcid.org/0000-0002-4958-652X)
- Tomoaki Matsumori (ORCID: https://orcid.org/0000-0002-1220-6546)
- Takeshi Kuwada (ORCID: https://orcid.org/0000-0002-9808-4139)
- Muneji Yasuda
- Ayako Hirata (ORCID: https://orcid.org/0000-0002-2548-8159)
- Ikuhisa Takimoto
- Koki Chikugo
- Kenji Sawada (ORCID: https://orcid.org/0000-0002-9352-5249)
- Shimpei Matsumoto (ORCID: https://orcid.org/0000-0001-6732-9116)
- Tsutomu Chiba
Institutions
- Kyoto University (JP)
- Kansai Electric Power Hospital (JP)
- Kobe University (JP)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2024-10-25
- DOI
- https://doi.org/10.1093/ibd/izae263
- Citations
- 2
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.10
Funders
- Japan Society for the Promotion of Science