Designing a time-dependent therapeutic strategy using CDK4/6 inhibitors in an intracranial ATRT model
Metronomic IT delivery of palbociclib enhances drug efficacy and safety, improves survival, and offers a promising treatment strategy for PBTs with CSF dissemination.
Authors
- Craig J. Thomas (ORCID: https://orcid.org/0000-0001-9386-9001)
- Ramana V. Davuluri (ORCID: https://orcid.org/0000-0002-7053-1064)
- Nadia Dahmane
- Madeline Laramee
- Mark M. Souweidane (ORCID: https://orcid.org/0000-0001-5627-4551)
- Brice Martin (ORCID: https://orcid.org/0000-0002-7366-1913)
- Sergio W. Guadix (ORCID: https://orcid.org/0000-0002-7602-6229)
- Abhinav Pandey (ORCID: https://orcid.org/0000-0002-7208-7059)
- Rekha Sathian (ORCID: https://orcid.org/0009-0005-5698-1981)
- Amy Wang (ORCID: https://orcid.org/0000-0002-1829-5877)
- Ishani Ray
Institutions
- National Institutes of Health (US)
- Memorial Sloan Kettering Cancer Center (US)
- Cornell University (US)
- National Cancer Institute (US)
- National Center for Advancing Translational Sciences (US)
- Neurological Surgery (US)
- Weill Cornell Medicine (US)
- Stony Brook University (US)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1093/neuonc/noae262
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44