Gonadal hormone abnormalities in young patients with first-episode schizophrenia
Our study reveals an overall gonadal hormone imbalance in young antipsychotic-naïve FES patients, highlighting sex differences at the onset of psychosis. Our study provides a foundation for further research into the role of gonadal hormones in the pathophysiology of SCH and the potential for personalized medicine approaches based on hormonal balance. Future studies were warranted to explore these differences and their implications for clinical practice to improve the treatment outcomes for individuals suffering from SCH.
Authors
- Fengchun Wu (ORCID: https://orcid.org/0000-0003-2817-2341)
- Meihong Xiu (ORCID: https://orcid.org/0000-0002-5125-8429)
- Shuangli Zhang (ORCID: https://orcid.org/0009-0002-7183-0637)
- Jing Liang (ORCID: https://orcid.org/0000-0003-0811-0223)
- Jindong Wang (ORCID: https://orcid.org/0000-0002-4833-0880)
- Qiang Hu
Institutions
- Peking University (CN)
- Quzhou City People's Hospital (CN)
- Qingdao Mental Health Center (CN)
- First Affiliated Hospital of Guangzhou Medical University (CN)
- Center for Translational Molecular Medicine (NL)
- Guangzhou Psychiatric Hospital (CN)
- Beijing HuiLongGuan Hospital (CN)
- Zhanjiang Experimental Station (CN)
- Guangdong 999 Brain Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- The International Journal of Neuropsychopharmacology
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1093/ijnp/pyae063
- Citations
- 6
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- National Natural Science Foundation of China
- Government of Jiangsu Province
- Basic and Applied Basic Research Foundation of Guangdong Province