Genetic Variants in Severe Hypertriglyceridemia Among Taiwanese Participants ― Insights From Genome-Wide Association and Whole-Exome Sequencing Analyses ―
Our study confirms the role of known genetic loci in triglyceride metabolism and hypertriglyceridemia while uncovering novel loci, offering new perspectives on lipid regulation and potential avenues for therapeutic advancements.
Authors
- Ming-Chieh Tsai (ORCID: https://orcid.org/0000-0002-9134-7653)
- Tzu‐Pin Lu (ORCID: https://orcid.org/0000-0003-3697-0386)
- Ta‐Chen Su (ORCID: https://orcid.org/0000-0001-7523-7166)
- Chih-Jun Lai (ORCID: https://orcid.org/0000-0002-4975-7501)
- Hsien‐Yu Fan (ORCID: https://orcid.org/0000-0001-9995-9497)
- Hsin‐Yin Hsu (ORCID: https://orcid.org/0000-0003-1734-0012)
- Hung‐Ju Lin (ORCID: https://orcid.org/0000-0003-2449-9072)
- Kuo‐Liong Chien (ORCID: https://orcid.org/0000-0003-4979-8351)
- Chiu‐Li Yeh (ORCID: https://orcid.org/0000-0001-8245-4601)
- Kuang Lin (ORCID: https://orcid.org/0000-0003-3017-6026)
- Po-Jui Lai
- Hsiu‐Ching Hsu
Institutions
- National Health Research Institutes (TW)
- National Taiwan University (TW)
- Mackay Memorial Hospital (TW)
- Neuropsychiatric Research Institute (US)
- National Taiwan University Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- Circulation Journal
- Published
- 2024-12-10
- DOI
- https://doi.org/10.1253/circj.cj-24-0491
- Citations
- 2
- Primary Topic
- Lipid metabolism and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.80