Multiethnic prevalence of the <i>APOL1</i> G1 and G2 variants among the Israeli dialysis population
These findings show that <i>APOL1</i> G1 and G2 allelic variants are present in populations previously not appreciated to possess recent sub-Saharan ancestry and suggest that a single G2 risk variant may confer increased risk for chronic kidney disease in certain population contexts.
Authors
- Revital Shemer
- Maayan Kagan
- Noam Hadar (ORCID: https://orcid.org/0000-0003-2483-2090)
- Ohad S. Birk (ORCID: https://orcid.org/0000-0003-1430-1296)
- Alla Shnaider
- Benaya Rozen‐Zvi
- Yair Anikster
- Haike Reznik‐Wolf
- Gil Chernin (ORCID: https://orcid.org/0000-0001-7514-156X)
- Keren Slabodnik-Kaner
- Danit Atias-Varon
- Omer Shlomovitz (ORCID: https://orcid.org/0000-0003-0757-3824)
- Edo Dotan
- Dana Levin (ORCID: https://orcid.org/0000-0002-5776-041X)
- Horia Stanescu (ORCID: https://orcid.org/0000-0001-5853-5030)
- Asaf Vivante
- Pazit Beckerman (ORCID: https://orcid.org/0000-0003-3061-6757)
- Gabriel Doctor (ORCID: https://orcid.org/0000-0001-8486-2334)
- Dan Dominissini (ORCID: https://orcid.org/0000-0003-1121-5130)
- Ronit Calderon‐Margalit (ORCID: https://orcid.org/0000-0002-3369-2758)
- Etty Kruzel-Davila (ORCID: https://orcid.org/0000-0002-7208-5707)
- Guy Chowers
- Yosef S. Haviv (ORCID: https://orcid.org/0000-0002-8875-6093)
- Karl Skorecki (ORCID: https://orcid.org/0000-0002-0900-3406)
- Noa Berar Yanay
- Dror Ben-Ruby
- Elon Pras
- A. Nahum
- Neta Mano
- Shany Avayou
- Yariv Atsmony
Institutions
- Ben-Gurion University of the Negev (IL)
- Bar-Ilan University (IL)
- Tel Aviv University (IL)
- Technion – Israel Institute of Technology (IL)
- Hebrew University of Jerusalem (IL)
- Sheba Medical Center (IL)
- Western Galilee Hospital (IL)
- Hadassah Medical Center (IL)
- Kaplan Medical Center (IL)
- Rabin Medical Center (IL)
- Soroka Medical Center (IL)
- Rambam Health Care Campus (IL)
- Hillel Yaffe Medical Center (IL)
- University Medical Center (US)
- Cancer Research Center (US)
- Centro de Investigación del Cáncer (ES)
- Edmond and Lily Safra Children's Hospital (IL)
- University College London (GB)
Publication Details
- Journal
- Clinical Kidney Journal
- Published
- 2024-12-06
- DOI
- https://doi.org/10.1093/ckj/sfae397
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.68
Funders
- Israel Science Foundation
- Tel Aviv University
- European Research Council