Navigating the challenge of high-grade cervical lesions (CIN3) in pregnancy: a near miss

In this case, a pregnant Indigenous woman presented with high-grade cervical lesions (high-grade squamous intraepithelial lesion (HSIL), cervical intraepithelial neoplasia grade 3 (CIN2-3) and was lost to follow-up for over 5 years, posing a unique management challenge. Despite higher regression rates in pregnant women, personalised care was crucial due to potential pregnancy-related intervention risks.This case underscores the complexities of managing high-grade cervical lesions in pregnancy and highlights the significant burden of cervical cancer within Aboriginal and Torres Strait Islander communities. It emphasises the urgent need for equitable screening access, patient-centred care and culturally sensitive education among vulnerable populations.Of particular note is the case's uniqueness, with the patient's CIN3 diagnosis persisting for over 5 years and spanning three pregnancies without definitive management. Post partum, a subsequent LLETZ revealed extensive HSIL (CIN3) involving ectocervical and endocervical margins. Due to margin involvement, the patient now requires ongoing surveillance, with continued risk of being lost to follow-up due to the factors described.

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Publication Details

Journal
BMJ Case Reports
Published
2024-12-01
DOI
https://doi.org/10.1136/bcr-2024-261808
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Navigating the challenge of high-grade cervical lesions (CIN3) in pregnancy: a near miss

Tithi Kulkarni, Anthony Fitch
BMJ Case Reports
Cervical Cancer and HPV Research
article

Navigating the challenge of high-grade cervical lesions (CIN3) in pregnancy: a near miss

Tithi Kulkarni, Anthony Fitch
article en

Abstract

In this case, a pregnant Indigenous woman presented with high-grade cervical lesions (high-grade squamous intraepithelial lesion (HSIL), cervical intraepithelial neoplasia grade 3 (CIN2-3) and was lost to follow-up for over 5 years, posing a unique management challenge. Despite higher regression rates in pregnant women, personalised care was crucial due to potential pregnancy-related intervention risks.This case underscores the complexities of managing high-grade cervical lesions in pregnancy and highlights the significant burden of cervical cancer within Aboriginal and Torres Strait Islander communities. It emphasises the urgent need for equitable screening access, patient-centred care and culturally sensitive education among vulnerable populations.Of particular note is the case's uniqueness, with the patient's CIN3 diagnosis persisting for over 5 years and spanning three pregnancies without definitive management. Post partum, a subsequent LLETZ revealed extensive HSIL (CIN3) involving ectocervical and endocervical margins. Due to margin involvement, the patient now requires ongoing surveillance, with continued risk of being lost to follow-up due to the factors described.

BMJ Case ReportsVol. 17(12)
WA Country Health Service (AU), North Metropolitan Health Service (AU), East Metropolitan Health Service (AU)
Quality Education
Openalex Percentile: Top 66%
Cervical Cancer and HPV Research
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