(307) EXPERT OPINIONS ON INTRACAVERNOSAL INJECTIONS AND THEIR LINK TO PEYRONIE’S DISEASE AND PENILE FIBROSIS: A SURVEY OF SUPS, GURS, AND SMSNA MEMBERS

Abstract Introduction The development of penile curvature is recognized as a potential adverse effect of intracavernosal injection (ICI) therapy. Literature often cites Peyronie’s disease as a possible consequence of ICI therapy. However, despite this widespread belief, there is a notable lack of data supporting a causal relationship between intracavernosal injection therapy and the onset of Peyronie’s disease. Objective To assess the current opinions of experts in sexual medicine, reconstructive urology, and prosthetic urology regarding the association between intracavernosal injection therapy and the development of Peyronie’s disease and penile fibrosis. Methods A 20-question survey was digitally distributed to the listservs of members of the Society of Urologic Prosthetic Surgeons (SUPS), Society of Genitourinary Reconstructive Surgeons (GURS) and the Sexual Medicine Society of North America (SMSNA). Responses were collected over an 8-month period allowing for up to three reminder emails to be sent from the participating societies. Results were then analyzed for descriptive statistics. Results A total of 100 surveys were completed. 70% of respondents completed fellowships with the most common being GURS. Respondents’ years in practice were evenly distributed with 49% above and 51% below ten years in practice. Overall, 68% of respondents stated that they counsel patients that ICI can cause Peyronie’s disease and 57% stated that they believe ICI causes corporal fibrosis. When looking at respondent demographics, 70% of fellowship trained respondents stated that they counsel patients that ICI can cause Peyronie’s compared to 57% of non-fellowship trained respondents. This was in contrast to priapism for which 40% of respondents stated that they counsel their patients that priapism may result in Peyronie’s disease with no significant difference in respondents’ completion of a fellowship. Conclusions The belief that ICI can cause Peyronie’s disease remains prevalent but not unanimous members of SMSMNA, GURS and SUPS. Urologists who have completed a fellowship are more likely to counsel patients on the risk of Peyronie’s and penile fibrosis with the use of ICI. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Boston Scientific and Coloplast.